Application of the ABC Algorithm in Parameter Estimation and Kinetic Model Selection in Propionic Fermentation

Document Type : Full Length Research Article

Authors

1 University of Para

2 Federal University of Para

3 Federal University of Amazonas

Abstract

A propionic acid fermentation process not only provides a more sustainable approach, but also opens the door to propionic acid production capacity in regions with limited petroleum supplies. With fermentation, low-cost substrates can be used, such as residual biomass; reducing their concentration in nature. This process becomes interesting because from it propionic acid is considered natural. Several models have already been developed to describe the dynamics of components such as: Microorganism (biomass), nutrients (substrate), metabolites (product). However, a challenge is how to define the model that best represents the kinetic term, and therefore, there are several models for this modeling. This article's novelty is the application of the Bayesian technique (Computational Bayesian Approximation) to estimate parameters and simultaneously select the best model. Model validation was carried out considering propionic fermentation regarding experimental data from the literature which one was selected the Andrews model as the best to predict the dynamic of biomass, substrate and product been the following parameters estimated μ_max= 0.192, ms = 0.005, mp = 0.017

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Articles in Press, Accepted Manuscript
Available Online from 22 August 2024
  • Receive Date: 17 September 2023
  • Revise Date: 25 July 2024
  • Accept Date: 22 August 2024